Because ganglions are sometimes mistaken for tumors, it's important to have a complete examination and, possibly, tests to confirm the diagnosis. Your podiatrist will ask you questions such as how long you've had the ganglion cyst, what kind of symptoms you're feeling, if it has changed in size, or if its size varies according to your activities.
During your exam, your podiatrist may do a translumination exam, shining a light through the swelling (usually you can see through a ganglion, but not through a tumor). When your foot is pressed, a ganglion feels spongy and the fluid moves from side to side.
If a bone spur is detected, x-rays may be needed. Fluid removal may be done to help determine the degree of the swelling and to decrease pain. To confirm a ganglion cyst, and MRI may be done, which reveals images of soft tissue and bone. Sometimes, special dyes may be injected into the area to show the outline of a ganglion.